Global Antidepressants Market Projected to Reach USD 35.6 Billion by 2031 Amid Increasing Mental Health Awareness and Drug Innovation

[London, 5th June 2025] – Clearview Market Insights (CVMI) forecasts that the global antidepressants market will grow from USD 20.5 billion in 2024 to USD 35.6 billion by 2031, with a compound annual growth rate (CAGR) of 8.4 percent. This growth is driven by greater mental health awareness, digital health access, and breakthrough pharmacological innovations.
Antidepressants are no longer viewed solely through a clinical lens—they now form part of broader mental wellness ecosystems,” said Dr. Ana Velasquez, mental health analyst at CVMI. "The next frontier lies in combining precision psychiatry with digital engagement and culturally responsive care.
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Key Numbers
- 2024 Market Value: USD 20.5 billion
- 2031 Market Value: USD 35.6 billion
- Seven-Year CAGR: 8.4 percent
- SSRIs Share (2024): 42%
- North America Market Share: 39%
Market Drivers
- Digital-first prescribing and therapy access
- Global destigmatization of mental illness
- Strong clinical data for treatment-resistant depression drugs
- Regulatory acceleration of novel psychotropic approvals
Company Highlights
- Pfizer scaled Zoloft generic access across Southeast Asia.
- Johnson & Johnson expanded Spravato trials for PTSD and suicidal ideation.
- Eli Lilly invested in digital platforms for personalized dose titration.
- Lundbeck acquired U.S.-based behavioral health firm to bolster real-world insights.
Regional Insights
- North America: High treatment rates and payer coverage for branded antidepressants.
- Europe: Widespread reimbursement and prescription of SSRIs and SNRIs.
- Asia-Pacific: Government-funded awareness campaigns and e-pharmacy expansion.
- Latin America & MEA: New mental health laws enabling wider antidepressant access.
2024–2025 Milestones
Quarter |
Event |
Outcome |
Q1 2024 |
FDA expands esketamine label |
Now includes acute suicidal ideation |
Q2 2024 |
WHO integrates MDD screening into PHC |
Boosts early diagnosis in 36 low-income countries |
Q3 2024 |
Eli Lilly partners on AI dosing engine |
Initial pilot shows 25% better remission rate |
Q1 2025 |
Psilocybin trial results published |
Demonstrated superior effect over SSRI comparator in Phase III |
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